Be sure to consult your healthcare provider prior to taking any new supplements, as some supplements may interact with your current medications.
Any medication or supplement can cause side effects. Add only one new supplement at a time to make sure you can safely take it without side effects.
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Reduces harmful tau phosphorylation
Helps prevent dental caries
Potentiates the
antidepressant effect of ketamine
Anti-inflammatory and antidepressant
Protects mitochondrial function and inhibits of apoptosis
Anti-diabetic
Protects the blood-brain barrier
Hepatoprotective (liver)
Neuroprotective
Antioxidant
Cholinesterase inhibitor -
thereby increasing acetylcholine (essential neurotransmitter)
Anti-inflammatory
Fights covid-19
Anti-cancer
Anti-diabetic
May improve sperm quality
Neuroprotective
Cholinesterase inhibitor -
thereby increasing acetylcholine (essential neurotransmitter)
Antioxidant
Anti-inflammatory
Anti-cancer
May help fight pulmonary fibrosis in post-Covid-19 patients
Antiviral (esp anti-Zika virus, and anti-Covid-19)
Antibacterial
Antidiabetic
Antioxidant
Anti-inflammatory
Antihypertensive
Hepatoprotective (liver)
Diuretic
*Improves lifespan by autophagia (in animal models)
Neuroprotective
Cholinesterase inhibitor -
thereby increasing acetylcholine (essential neurotransmitter)
Anti-amyloid (by up-regulating circHDAC9)
Improves mitochondrial function
Anti-cholesterol
Antioxidant
Anti-inflammatory
Anti-cancer
Anti-diabetic; increases insulin sensitivity
*Readily crosses the blood-brain barrier
Neuroprotective
Cholinesterase inhibitor -
thereby increasing acetylcholine (essential neurotransmitter)
Anti-amyloid
Promotes mitochondrial health
Antiviral
Anti-covid-19
Decreases homocysteine levels
Necessary for many enzymatic functions
Red blood cell production
*Metformin can result in B12 deficiency
Neuroprotective
anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Helps eye health; cataracts
Strongly anticancer
*Protects telomeres (associated with longer life)
*(B-cryptoxanthin) Slower biologic aging
Anti-amyloid
Antioxidant
Cardiprotective
anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Helps maintain and normalized vital mitochondrial function
Note that mitochondrial function is impaired by lipid-lowering agents (statins)
*Can inhibit effects of blood thinners
Antioxidant
Anti-inflammatory
helps immune function
Anti-cancer
Anti-diabetic
Promotes healthy mitochondrial function
Improves Covid-19 outcomes
Helpful in multiple sclerosis
Helps diabetic retinopathy
Helps Nonalcoholic fatty liver disease (NAFLD)
Essential for bone health
*Increases telomere length & decreases biologic age
NOTE: can be toxic in high doses; may increase risk of heart disease (get your vitamin D blood level checked)
Neuroprotective
Anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Antioxidant
Anti-inflammatory
Helps fight covid-19
anti-viral
Powerful anti-cancer
stimulates nerve synaptic formation
stimulates neurogenesis in the hippocampus
Helps osteoporosis
Decreases insulin resistance
Decreases fraility
*Senolytic (extends lifespan)
*Decreases polymerase I (very unique; extends lifespan)
Anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Antioxidant
Anti-inflammatory
Beneficial for gut microbiome & helps restore gut permeability to normal
Strong anticancer
Pulmoprotective (lung)
Retinoprotective (eye retina)
Suppresses tardive dyskinesia (TD)
Helps with kidney fibrosis
Antidepressant
*Improves blood-brain barrier permeability (important for curcumin brain penetration)
A natural human amino acid that decreases with age
Antioxidant
Vital for the production of numerous human chemicals
Antidiabetic
Helps prevent metabolic syndrome
Cardioprotective
Promotes endothelial (blood vessel) health*Helps
Helps promote longevity!
Neuroprotective
Anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Antioxidant
Anti-inflammatory
Helps with COPD
Anti-cancer
Anti-diabetic
Anti-microbial
Anti-viral & possibly helps with covid-19
Antihypertensive
improves cardiovascular disease
Helps with menopause
Mitigates alcohol-induced liver damage
Helps with metabolic syndrome
*Lowers epigenetic age
Neuroprotective
Helps treat nonalcoholic steatohepatitis (NASH)
Antioxidant
Anti-inflammatory
Improves gut microbiota
Fights atherosclerosis
Antiaging thorough autophagia
Putative aphrodisiac
Essential for blood coagulation
Antioxidant
Anti-inflammatory
Helps with Asthma
Anti-cancer
Anti-microbial
Anti-viral & possibly helps with covid-19
Supports cardiovascular health
Supports bone metabolism
Supports gut health and IBS
Can help treat hyperlipidemia
NOTE: Statins impair vitamin K metabolism - and so taking supplemental vitamin K seems logical if you are taking Statins
Neuroprotective
Anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Antioxidant
Anti-inflammatory
Helps fight covid-19
anti-viral
Anti-cancer
stimulates nerve synaptic formation
stimulates neurogenesis in the hippocampus
Improves mitochondrial function
Neuroprotective
Antioxidant
Anti-inflammatory
Anti-cancer
Anti-diabetic
Cardioprotective/antiarrhythmic
Hepatoprotective
Anti-diabetic
Improves bone health
Possibly helps migraines
May help insomnia
May help with leg cramps
*Threonate improved anti-Alzheimer's function of atorvastatin in one study
**Magnesium L-Threonate (best brain levels of Mg++)
Regulates sleep patterns & circadian rhythm
Neuroprotective
Antioxidant
Anti-bacterial
Anti-viral
Anti-parasitic
Anti- sepsis
Anti-obesity
Immunoregulatory
Anti-cancer; breast CA
Neuroprotective
Antioxidant
Anti-inflammatory
Anti-bacterial
Anti- sepsis
Improves joint health and bone formation
Reduces facial signs of aging and protects against photoaging
Helps with fatty liver
Anti-diabetic
Increases HDL ("good cholesterol")
Potentially reduces hair loss
May protect against alcohol-induced brain injury
May help with periodontal disease
Anti-cancer
Neuroprotective
Antioxidant
Anti-biofilm
Anti-inflammatory
Protects against liver damage after acetaminophen (Tylenol, Paracetamol) overdose
Helps respiratory diseases (COPD, emphysema, pulmonary fibrosis and hypertension; asthma, silicosis)
Protects against air pollution inducted brain damage
Mucolytic effects (similar to Mucinex)
Helps treat/prevent covid-19
**Increases OXR1, mimicking dietary restriction, which is known to increase lifespan! Promotes longevity
Take with glycine for longevity
Neuroprotective
Antioxidant
Anti-inflammatory
Improves gut microbiota
Improves mitochondrial function & increases energy
Increases NAD+
Improves survival of those with sepsis
May improve gut stem cells
May help with knee osteoarthritis
When combined with resveratrol, protective against wood smoke
Anti-diabetic; helps with diabetic neuropathy
May improve lifespan
Caution: may increase blood pressure
**Read this article to determine if you should take Fish Oil supplements (can be harmful in certain individuals)
Antioxidant
Anti-inflammatory
Anti-cancer
Anti-diabetic
Cardioprotective
Decreases hypertriglyceridemia
Helps with arthritis
Helps with depression & bipolar disorder
Hepatoprotective
Helps with hypertension
Anti-amyloid
Antioxidant
Antiviral - possibly helps with covid-19
Anti-inflammatory
Helps with hypertension
Cardioprotective
Anti-diabetic
Anticancer
Decreases neuroinflammation
Anti-amyloid
Anti-oxidant
Improves cognition (MMSE score)
Anti-diabetic (decreases insulin)
Anti-cholesterol
Restores digestive balance
Strains shown to be neuroprotective:
1. Bifidobacterium longum 2. Bifidobacterium infantis 3. Bifidobacterium lactis
4. Bifidobacterium breve 5. Lactobacillus acidophilus
6. Lactobacillus rhamnosus 7. Lactobacillus plantarum 8. Lactobacillus paracasei (and antiaging)
Neuroprotective
Antioxidant
Anti-inflammatory
Anti-cancer
Anti-diabetic; improves metabolic syndrome
Hepatoprotective
Cardioprotective
Antifungal
Improves mitochondrial function
Decreases stress hormones (cortisol)
*Metabolite of resveratrol, but more potent in some effects
Neuroprotective
Anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Anti-amyloid
*Binds to ApoE4 (Apolipoprotein E4)
Antioxidant
Anti-inflammatory
Anti-cancer
Anti-viral
Helps with osteoporosis
Anti-microbial
Lowers cholesterol
Lowers blood pressure
Improves endothelial (blood vessel) function
Helps treat myocardial infarctions (MIs)
Helps prevent/treat Covid-19
*One component of olive oil and honey
*Senolytic (prolongs life)
Neuroprotective
Anticholinesterase inhibitor - thereby increasing acetylcholine (essential neurotransmitter)
Anti-amyloid (by up-regulating circHDAC9)
Improves mitochondrial function
Antioxidant
Anti-inflammatory
Strongly anti-cancer (inhibits the MDM2 p51 pathway)
Anti-viral
Anti-diabetic/improves insulin resistance
Helps with psoriasis
Beneficial effects on gut microbiota
Cardioprotective and protects endothelium
Helps with pulmonary fibrosis
Hepatoprotective (liver)
Helps knee osteoarthritis
May help prevent/treat Covid-19
Promotes mitochondrial function
*Increases SIRT 1
*Readily crosses the blood-brain barrier
*Senolytic (prolongs life; preserve telomere length)
Anti-amyloid
Helps treat COPD
Antioxidant
Anti-inflammatory
Promotes mitochondrial biogenesis
Anti-cancer
May help with IBS
Helps with NASH
Cardioprotective
Increases ketones
May help with MRSA pneumonia
May help with prostatitis
Neuroprotective
Improves cognition in those with dementia
Fights osteoporosis
Fights sarcopenia (abnormal muscle loss in the aged)
Antioxidant
Anticancer
Cardioprotective
Anti-inflammatory
Fights rheumatoid arthritis
*Improves lifespan by autophagia (in animal models)
Improves mitochondrial function
Neuroprotective
Antioxidant
Anti-inflammatory; decreases hs-C-reactive protein
Anti-cancer
Anti-diabetic; decreases insulin resistance
Helps hypertension
Decreases cholesterol
helps with muscle cramps
Contains many vitamins and nutrients
Neuroprotective
Antioxidant
Anti-inflammatory
Anti-diabetic; decreases insulin resistance
Anti-obesity
Hepatoprotective (liver)
Lipid-lowering
Anti-obesity
Level correlated with hippocampal brain volume (memory)
Supports mitochondrial function (energy)
Helps prevent DNA damage
*Senolytic (prolongs life)
*Inhibits chromosomal telomerase (prolongs life)
Natural ammino acid
Blood levels lower in people with Alzheimer's
Often part of "energy" drink formulas
anti-biofilm (like NAC)
Anti-atherogenic properties
Antimycobacterial (TB)
Sleep promoting (take at bedtime)
Strong - anticancer - breast
Anti-diabetic (increases GLP-1 similar to Ozempic = Wegovy, Zepbound)
Anti-obesity (high dose)
Hepatoprotective (liver)
Nephroprotective (kidney)
Anti-viral (including SARS-CoV-2
Promotes wound healing
*emulates the effects of intermittent fasting and prolongs life
I1 receptor agonist (like rilmenidine)
promotes Nff2 activity
boosts NAD+
Neuroprotective
Antioxidant
Anti-inflammatory
Anti-microbial
Powerful anticancer agent
Anti-diabetic; decreases insulin resistance
Improves mitochondrial function
Helps arthritis
Improves cardiovascular function
Hepatoprotective (liver)
Helps kidney function
Improves longevity
Helps with IBS
*Has poor bioavailability - should be co-administered with Ginkgo Biloba (which improves blood-brain barrier transport)
*Use with caution if taking blood thinners or NSAIDS
Helicobacter pylori
(H. pylori) infects more than 50% of the population in the world, mostly in developing countries
Helicobacter pylori is a pathogenic bacterium that causes gastritis and gastric carcinoma (cancer).
Symptoms of infection:
An ache or burning pain in your stomach (abdomen)
Stomach pain that may be worse when your stomach is empty
Nausea
Loss of appetite
Frequent burping
GermGuardian Air Purifier for Home, Large Rooms, H13 HEPA [High Efficiency Particulate Air] Filter, Removes Dust, Allergens, Smoke, Pollen, Odors, Mold, UV-C Light Helps Reduce Germs
This is what Dr. Frank uses in his home. One on every floor! Air purifiers run 24/7!
Filters are easy to change & a light comes on telling you when you need to change filters
Body-Mass Index (BMI)
Ideal body weight
Body fat
Calorie counter
Measure your estimated visceral fat by calculating your waist-to-height ratio
Major article on aroma therapy
Major aromas: rose, lemon, orange, lavender, ginger, turmeric, and others.
Olfactory dysfunction (impaired sense of smell) may predate clinical symptoms of Alzheimer's dementia
Olfactory dysfunction is also frequently found in people infected with SARS-CoV-2 (Covid-19)
Test your sense of smell with Scentawave
Caffeine inhibits tau formation - neuroprotective
Coffee Inhibits beta amyloid - neuroprotective
Phenylindanes inhibit both beta amyloid and tau
(higher amounts produced from dark roast coffee)
inhibits
Butyrylcholinesterase (BChE) thereby increasing acetylcholine (essential neurotransmitter)
Anti-cancer (caffeine)
anti-diabetic
Anti-inflammatory, especially when combined with milk
Supports cardiovascular function
May decrease the risk of stroke (but monitor your blood pressure)
*Recommend drinking 2-4 cups per day. Higher amounts may increase the risk of dementia!